Certified RNase/DNase-Free Products across all scales
FreeANASE™ ensures certified RNase- and DNase-free Single-Use Assemblies for sensitive RNA- and DNA-based Applications. Our technology guarantees the highest standard of purity and contamination control — from laboratory-scale research to commercial biopharmaceutical manufacturing.
We supply Single-Use Components and Assemblies certified to be RNase- and DNase-free.
This essential quality standard is maintained across:
- Research Laboratories
- Pilot-scale Facilities
- GMP Production Environments
FreeANASE™ protects RNA and DNA Integrity in the manufacturing for highly sensitive biological products.
Innovative Non-Thermal Plasma Technology by 3CON
RNase/DNase Inactivation
3CON’s FreeANASE™ Technology utilizes a highly innovative non-thermal plasma process to inactivate RNase and DNase on any product-contact surface.
This advanced method enables:
- Simultaneous Treatment of multiple components
- Uniform Surface Inactivation
- Chemical-free Decontamination
- Compatibility with diverse Single-Use Materials
FreeANASE™ as a Service
Certified RNase/DNase-free consumables are produced under controlled cleanroom conditions. Processing takes place in qualified ISO 6 and ISO 7 environments to ensure reliable nuclease-free integrity.
Your components are returned:
- Certified RNase-/DNase-free
- Handled under strict Contamination Control
- Ready for immediate, sterile deployment
Optional sterilization services are available to provide an additional layer of safety.
This is how FreeANASE™ works
- STEP 1: Send your Single-Use Assemblies or components to 3CON
- STEP 2: RNase Inactivation Treatment in our certified ISO 6/7 cleanroom.
- STEP 3: Optional sterilization upon request for complete assembly safety.
- STEP 4: Return of certified RNase-free (and optionally sterile) products — directly to you or your customer.
Regulatory Compliance & Quality Assurance
FreeANASE™ is built around strict quality and regulatory standards:
- Patent-Pending Technology:
Non-thermal plasma-based RNase/DNase Inactivation. - Certified RNase-/DNase-Free Components:
Ensuring maximum integrity in sensitive applications. - GMP & GEP Alignment:
Full adherence to Good Manufacturing Practice and Good Engineering Practice guidelines. - Chemical-Free Process:
Complete RNase/DNase Inactivation without harsh chemicals, protecting product quality and reducing process risk.
- ISO Compliance:
ISO 14644 (Cleanroom Standards – ISO 6/7)
ISO 11137 (Sterility validation where applicable)
ISO 9001 (Quality Management System)
Applications of FreeANASE™
- Biotechnology & Research
Critical for RNA/DNA workflows and highly sensitive assays requiring contamination-free environments. - Pharmaceutical Production
Ensures RNase-/DNase-free conditions for RNA therapeutics, mRNA manufacturing, and gene therapy production. - Quality Assurance (QA)
Supports risk minimization and validated contamination control across the value chain. - Process Control
Enables consistent, verifiable RNase management for reproducible manufacturing outcomes.
